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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CDC16
All Species:
34.24
Human Site:
S124
Identified Species:
50.22
UniProt:
Q13042
Number Species:
15
Phosphosite Substitution
Charge Score:
-0.13
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q13042
NP_001072113.1
620
71656
S124
P
S
S
D
W
E
M
S
Q
S
S
I
K
S
S
Chimpanzee
Pan troglodytes
XP_001141335
657
75449
S161
P
S
S
D
W
E
M
S
Q
S
S
I
K
S
S
Rhesus Macaque
Macaca mulatta
XP_001089625
620
71585
S124
P
S
S
D
W
E
M
S
Q
S
S
I
K
S
S
Dog
Lupus familis
XP_848577
620
71476
S124
P
S
S
D
W
E
M
S
Q
S
S
I
K
S
S
Cat
Felis silvestris
Mouse
Mus musculus
Q8R349
620
71442
S124
P
S
S
D
W
E
M
S
Q
S
S
I
K
S
S
Rat
Rattus norvegicus
NP_001019915
620
71343
S124
P
S
S
D
W
E
M
S
Q
S
S
I
K
S
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001513048
324
37070
Chicken
Gallus gallus
NP_001006265
624
72618
S124
S
T
T
D
W
E
M
S
Q
S
S
I
K
S
S
Frog
Xenopus laevis
NP_001087093
621
71792
S122
P
S
G
E
W
Q
M
S
Q
S
S
I
K
S
S
Zebra Danio
Brachydanio rerio
NP_001032466
616
70436
S124
I
V
K
D
W
E
M
S
P
S
S
I
N
S
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_623316
640
73022
A126
R
A
D
I
L
E
D
A
P
K
N
V
Q
S
S
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001203133
551
62760
K82
E
M
K
L
E
D
Q
K
D
E
L
D
R
I
P
Poplar Tree
Populus trichocarpa
XP_002331799
542
62607
L72
S
K
I
V
L
R
D
L
R
F
R
Y
L
A
A
Maize
Zea mays
NP_001141501
580
66070
R109
L
N
N
S
R
L
L
R
D
L
R
F
R
F
L
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
NP_565188
543
61743
L72
S
K
I
V
L
R
D
L
R
F
R
Y
L
A
A
Baker's Yeast
Sacchar. cerevisiae
P09798
840
94974
G353
T
S
Q
P
V
T
D
G
G
I
K
M
E
S
S
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
94.3
99.3
97.9
N.A.
95.4
95.9
N.A.
48.2
91.5
88.8
79.1
N.A.
N.A.
49.6
N.A.
49
Protein Similarity:
100
94.3
99.6
98.5
N.A.
97.9
98
N.A.
50.1
95.8
95.8
87.9
N.A.
N.A.
68.1
N.A.
66.7
P-Site Identity:
100
100
100
100
N.A.
100
100
N.A.
0
80
80
66.6
N.A.
N.A.
20
N.A.
0
P-Site Similarity:
100
100
100
100
N.A.
100
100
N.A.
0
93.3
93.3
66.6
N.A.
N.A.
53.3
N.A.
13.3
Percent
Protein Identity:
35.8
36.9
N.A.
38.2
23.8
N.A.
Protein Similarity:
52.1
54.6
N.A.
54.3
41.5
N.A.
P-Site Identity:
0
0
N.A.
0
20
N.A.
P-Site Similarity:
20
26.6
N.A.
20
33.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
7
0
0
0
0
0
7
0
0
0
0
0
13
13
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
7
50
0
7
25
0
13
0
0
7
0
0
0
% D
% Glu:
7
0
0
7
7
57
0
0
0
7
0
0
7
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
13
0
7
0
7
0
% F
% Gly:
0
0
7
0
0
0
0
7
7
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
7
0
13
7
0
0
0
0
0
7
0
57
0
7
0
% I
% Lys:
0
13
13
0
0
0
0
7
0
7
7
0
50
0
0
% K
% Leu:
7
0
0
7
19
7
7
13
0
7
7
0
13
0
7
% L
% Met:
0
7
0
0
0
0
57
0
0
0
0
7
0
0
0
% M
% Asn:
0
7
7
0
0
0
0
0
0
0
7
0
7
0
0
% N
% Pro:
44
0
0
7
0
0
0
0
13
0
0
0
0
0
7
% P
% Gln:
0
0
7
0
0
7
7
0
50
0
0
0
7
0
0
% Q
% Arg:
7
0
0
0
7
13
0
7
13
0
19
0
13
0
0
% R
% Ser:
19
50
38
7
0
0
0
57
0
57
57
0
0
69
69
% S
% Thr:
7
7
7
0
0
7
0
0
0
0
0
0
0
0
0
% T
% Val:
0
7
0
13
7
0
0
0
0
0
0
7
0
0
0
% V
% Trp:
0
0
0
0
57
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
13
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _